This report documents our research and proposal for the “Design of a Scalable Framework of Lunar Habitats – an activity funded by the Discovery element in the European Space Agency as part of their OSIP (Open Space Innovation Platform) Off-Earth Manufacturing and Construction Campaign. The aim of the study was to develop a scalable, holistic design framework for permanent human habitation on the Moon, embedding key solutions for environmental protection and mitigation, construction methodology and assembly of a scalable architecture, life support and an overall mission architecture. To ensure a holistic and integrated scheme, Hassell has partnered with Cranfield University’s Master of Astronautics and Space Engineering Module which brings expertise around the system and mission architecture for our design. Together, we have conducted a comprehensive review and synthesis of technical requirements and existing space infrastructure developments to form the basis of our design solution. This approach differs from conventional design models, ensuring participation and integration of industry experts and practitioners from project inception.