During the project activities, the authors proposed a conceptual framework, which utilizes resources available in situ through the chemical and physical processes associated with agriculture; the soil and CO2 (if present) are transformed into fibrous plant matter, harvested and finally converted into mechanical and structural components. In order to provide a comparison, the authors investigated the use of regolith and wood as fillers in the matrix of 3D printable polymers. The authors tested these materials printability both at atmospheric pressure and in vacuum. According to both these scenarios, in a hypothetical settlement mission the bare minimum material and equipment is shipped from Earth to some suitable, i.e. material rich, location on the proto-planet of choice. This constitutes the basic building block to erect a precursor base. Furthermore, the authors have studied the process of assembling modular 3D printable components with the aid of a robotic manipulator. This is another building block that enables the construction of complex structures on the surface of the Moon or on any other planetary surface.